A model for prostate brachytherapy planning with sources and needles position optimization
2014
Operations Research for Health Care
1
3
31-39
No
NA
Low dose rate brachytherapy is one of the treatments for localized prostate cancer. In the prostate case, the radioactive sources are located through needles into the organ tissue. The sources are placed in a way that enough dose is delivered to treat the tumor while preserving the surrounding healthy tissue. Since there are several location possibilities for tens of sources in use and constraints among them, the problem where to locate the sources becomes difficult. To solve the problem, this work proposes a mathematical model based on the previous o